A Hyper Potion is a type of medicine used to heal a Pokémon by 200 HP.
Five Super Potions can be used to craft a Hyper Potion. This heals fewer HP in total, but can be used in a single battle turn rather than five turns.
Two Hyper Potions can be used to craft a Max Potion.
Before Pixelmon reforged, the Hyper Potion could be crafted in the following way:
(It was removed due to many held items being far too easy to make.)