NodeCraft
X Defense
From Pixelmon Wiki
An X Defense is a type of medicine that temporarily raises a Pokémon's Defense by one stage while in battle. Before Pixelmon Reforged, it could be obtained from shopkeepers and as a tier 1 special drop. It is a possible drop from common boss Pokémon.
Crafting
X Defense can be crafted by using a Ganlon Berry in a Brewing stand when supplied with 1-3 water bottle(s).
